The Wollman lab studies spatio-temporal regulation of self-organization processes during the innate immune response to stress. At the Intra-cellular scale we study how signaling network control the organization of the actin cytoskeleton in chemotaxis, phagocytosis and secretion. At the inter-cellular scale we study how cells utilize paracrine signaling to coordinate their functions with one another to produce a coherent and robust response to stress. In the lab we combine microscopy, computational image analysis and mathematical modeling.
Bioinformatics and Systems Biology
BISB Research Area(s)
Brief Research Description
Self-Organization in biological systems