Drug resistance and population analysis of Mozambique malaria samples

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Project Description

Malaria remains a major problem for 40% of the world's population and drug resistance is widespread.  One mechanism for identifying drug resistance determinants is by identifying regions that show unexpected homozygosity in whole genome sequences.  The rotation student will work with physician scientists to align short read sequences to the P. falciparum genome, call variants, annotate variants, run population genetics analyses and produce reports.