Our lab is interested in how the human brain is assembled. We use genetic strategies to explore causes of human disease and then link these genes to function using model systems. We are focused on diseases like mental retardation, epilepsy and autism, where brain development is disrupted. We have two full time bioinformatics (graduate student and staff programmer) developing computational solutions, database design and machine learning paradigms for large datasets in the area of genome sequencing.
Director of Neurogenetics
Bioinformatics and Systems Biology
BMI Research Area(s)
Brief Research Description
Autism, Whole genome sequencing, Epigenome, Single cell sequencing, Gene-environment interactions, Somatic mosaicism, Systems biology, Protein interactions