Kelly Frazer

Faculty Status
Active
Title
Professor
Title 2
Director
Email
kafrazer@health.ucsd.edu
Phone
(858) 246-0208
Track(s)
Bioinformatics and Systems Biology
Biomedical Informatics
Department
Brief Research Description
Using iPSCs for genetic analyses, GWAS, QTL analyses, bioinformatic approaches to understanding human disease, single-cell analyses
Lab Description

Welcome to the Frazer Lab! We are using two complementary approaches to achieve our goal of identifying and characterizing functional human genetic variants. Our first approach utilizes iPSCORE, a resource that was generated to enable both familial and association-based genetic studies of molecular and physiological phenotypes in induced pluripotent stem cells (iPSCs) and derived cell types. Our second approach involves conducting association studies in well-characterized cohorts with the goal of identifying variants that play roles in human disease and to assess their contributions to disease pathogenesis, progression, and prognosis.