Our overall goal is to understand complex genetic variants that underlie human disease. We are particularly interested in repetitive DNA variants known as short tandem repeats (STRs) as a model for complex variation. Our work focuses on developing computational tools for analyzing and visualizing complex variation from large-scale sequencing data and applying these tools to learn about the contribution of repetitive variation to human disease.
Bioinformatics and Systems Biology
BISB Research Area(s)
Brief Research Description
Contribution of complex genetic variation to human phenotypes