Student Publications

Zaramela LS, Martino C, Alisson-Silva F, Rees SD, Diaz SL, Chuzel L, Ganatra MB, Taron CH, Secrest P, Zuñiga C, Huang J, Siegel D, Chang G, Varki A, Zengler K. "Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates." Nat Microbiol. 2019. PubMed DOI

Zhang K, Wang M, Zhao Y, Wang W. "Taiji: System-level identification of key transcription factors reveals transcriptional waves in mouse embryonic development." Sci Adv. 2019;5(3):eaav3262. PubMed PMC DOI

Zhang Y, Li T, Preissl S, Amaral ML, Grinstein JD, Farah EN, Destici E, Qiu Y, Hu R, Lee AY, Chee S, Ma K, Ye Z, Zhu Q, Huang H, Fang R, Yu L, Izpisua Belmonte JC, Wu J, Evans SM, Chi NC, Ren B. "Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells." Nat Genet. 2019;51(9):1380-1388. PubMed PMC DOI

Zhou J, Ma J, Chen Y, Cheng C, Bao B, Peng J, Sejnowski TJ, Dixon JR, Ecker JR. "Robust single-cell Hi-C clustering by convolution- and random-walk-based imputation." Proc Natl Acad Sci U S A. 2019;116(28):14011-14018. PubMed PMC DOI

Ai R, Laragione T, Hammaker D, Boyle DL, Wildberg A, Maeshima K, Palescandolo E, Krishna V, Pocalyko D, Whitaker JW, Bai Y, Nagpal S, Bachman KE, Ainsworth RI, Wang M, Ding B, Gulko PS, Wang W, Firestein GS. "Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes." Nat Commun. 2018;9(1):1921. PubMed PMC DOI

Al-Bassam MM, Kim JN, Zaramela LS, Kellman BP, Zuniga C, Wozniak JM, Gonzalez DJ, Zengler K. "Optimization of carbon and energy utilization through differential translational efficiency." Nat Commun. 2018;9(1):4474. PubMed PMC DOI

Autran CA, Kellman BP, Kim JH, Asztalos E, Blood AB, Spence ECH, Patel AL, Hou J, Lewis NE, Bode L. "Human milk oligosaccharide composition predicts risk of necrotising enterocolitis in preterm infants." Gut. 2018;67(6):1064-1070. PubMed DOI

Bauman N, Akella S, Hann E, Morey R, Schwartz AS, Brown R, Richardson TH. "Next-Generation Sequencing of Haematococcus lacustris Reveals an Extremely Large 1.35-Megabase Chloroplast Genome." Genome Announc. 2018;6(12). PubMed PMC DOI

Beyter D, Lin MS, Yu Y, Pieper R, Bafna V. "ProteoStorm: An Ultrafast Metaproteomics Database Search Framework." Cell Syst. 2018;7(4):463-467.e6. PubMed PMC DOI

Bluemel S, Wang L, Martino C, Lee S, Wang Y, Williams B, Horvath A, Stadlbauer V, Zengler K, Schnabl B. "The Role of Intestinal C-type Regenerating Islet Derived-3 Lectins for Nonalcoholic Steatohepatitis." Hepatol Commun. 2018;2(4):393-406. PubMed PMC DOI

Brunk E, Sahoo S, Zielinski DC, Altunkaya A, Dräger A, Mih N, Gatto F, Nilsson A, Preciat Gonzalez GA, Aurich MK, Prlić A, Sastry A, Danielsdottir AD, Heinken A, Noronha A, Rose PW, Burley SK, Fleming RMT, Nielsen J, Thiele I, Palsson BO. "Recon3D enables a three-dimensional view of gene variation in human metabolism." Nat Biotechnol. 2018;36(3):272-281. PubMed PMC DOI

Bui N, Huang JK, Bojorquez-Gomez A, Licon K, Sanchez KS, Tang SN, Beckett AN, Wang T, Zhang W, Shen JP, Kreisberg JF, Ideker T. "Disruption of NSD1 in Head and Neck Cancer Promotes Favorable Chemotherapeutic Responses Linked to Hypomethylation." Mol Cancer Ther. 2018;17(7):1585-1594. PubMed PMC DOI

Her HL, Wu YW. "A pan-genome-based machine learning approach for predicting antimicrobial resistance activities of the Escherichia coli strains." Bioinformatics. 2018;34(13):i89-i95. PubMed PMC DOI

Her HL, Wu YW. "A pan-genome-based machine learning approach for predicting antimicrobial resistance activities of the Escherichia coli strains." Bioinformatics. 2018;34(13):i89-i95. PubMed PMC DOI

Huang JK, Carlin DE, Yu MK, Zhang W, Kreisberg JF, Tamayo P, Ideker T. "Systematic Evaluation of Molecular Networks for Discovery of Disease Genes." Cell Syst. 2018;6(4):484-495.e5. PubMed PMC DOI

Huang JK, Jia T, Carlin DE, Ideker T. "pyNBS: a Python implementation for network-based stratification of tumor mutations." Bioinformatics. 2018;34(16):2859-2861. PubMed PMC DOI

Kavvas ES, Seif Y, Yurkovich JT, Norsigian C, Poudel S, Greenwald WW, Ghatak S, Palsson BO, Monk JM. "Updated and standardized genome-scale reconstruction of Mycobacterium tuberculosis H37Rv, iEK1011, simulates flux states indicative of physiological conditions." BMC Syst Biol. 2018;12(1):25. PubMed PMC DOI

Kuo CC, Chiang AW, Shamie I, Samoudi M, Gutierrez JM, Lewis NE. "The emerging role of systems biology for engineering protein production in CHO cells." Curr Opin Biotechnol. 2018;51:64-69. PubMed PMC DOI

Link VM, Duttke SH, Chun HB, Holtman IR, Westin E, Hoeksema MA, Abe Y, Skola D, Romanoski CE, Tao J, Fonseca GJ, Troutman TD, Spann NJ, Strid T, Sakai M, Yu M, Hu R, Fang R, Metzler D, Ren B, Glass CK. "Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function." Cell. 2018;173(7):1796-1809.e17. PubMed PMC DOI

Lu J, Cao X, Zhong S. "A likelihood approach to testing hypotheses on the co-evolution of epigenome and genome." PLoS Comput Biol. 2018;14(12):e1006673. PubMed PMC DOI

Luo C, Rivkin A, Zhou J, Sandoval JP, Kurihara L, Lucero J, Castanon R, Nery JR, Pinto-Duarte A, Bui B, Fitzpatrick C, O'Connor C, Ruga S, Van Eden ME, Davis DA, Mash DC, Behrens MM, Ecker JR. "Robust single-cell DNA methylome profiling with snmC-seq2." Nat Commun. 2018;9(1):3824. PubMed PMC DOI

Ma J, Yu MK, Fong S, Ono K, Sage E, Demchak B, Sharan R, Ideker T. "Using deep learning to model the hierarchical structure and function of a cell." Nat Methods. 2018;15(4):290-298. PubMed PMC DOI

Marty R, de Prisco N, Carter H, Font-Burgada J. "MHC-I genotype drives early immune selection of oncogenic mutations." Mol Cell Oncol. 2018;5(2):e1409863. PubMed PMC DOI

Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, Park HW, Wang X, Yu FX, Chien S, Wang CY, Ren B, Engler AJ, Guan KL. "RAP2 mediates mechanoresponses of the Hippo pathway." Nature. 2018;560(7720):655-660. PubMed PMC DOI

Miao Y, Ajami NE, Huang TS, Lin FM, Lou CH, Wang YT, Li S, Kang J, Munkacsi H, Maurya MR, Gupta S, Chien S, Subramaniam S, Chen Z. "Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function." Nat Commun. 2018;9(1):292. PubMed PMC DOI