Student Publications

Students in the Graduate Bioinformatics & Systems Biology Program have authored numerous publications; their names are highlighted in red on the list below. Program faculty are highlighted in green.

Students, please keep the Graduate Program Coordinator appraised of your new publications and any inaccuracies or omissions on this list. Most articles are indexed in PubMed; please provide the PubMed ID numbers (PMID) for your articles if available, to expedite the maintenance of this list.


Van Nostrand EL, Pratt GA, Shishkin AA, et al. "Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)." Nat. Methods. 2016;13(6):508-14.
Sauls JT, Li D, Jun S. "Adder and a coarse-grained approach to cell size homeostasis in bacteria." Curr. Opin. Cell Biol.. 2016;38:38-44.
Brandler WM, Antaki D, Gujral M, et al. "Frequency and Complexity of De Novo Structural Mutation in Autism." Am. J. Hum. Genet.. 2016;98(4):667-79.
Rentas S, Holzapfel NT, Belew MS, et al. "Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells." Nature. 2016;532(7600):508-11.
Baker CW, Miller CR, Thaweethai T, et al. "Genetically Determined Variation in Lysis Time Variance in the Bacteriophage φX174." G3 (Bethesda). 2016;6(4):939-55.
Brunk E, Mih N, Monk J, et al. "Systems biology of the structural proteome." BMC Syst Biol. 2016;10:26.
Yurkovich JT, Palsson BO. "Solving Puzzles With Missing Pieces: The Power of Systems Biology." Proceedings of the IEEE. 2016;104(1):2-7. URL 


Hung T, Pratt GA, Sundararaman B, et al. "The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression." Science. 2015;350(6259):455-9.
Shen JPaul, Srivas R, Gross A, et al. "Chemogenetic profiling identifies RAD17 as synthetically lethal with checkpoint kinase inhibition." Oncotarget. 2015;6(34):35755-69.
Wu J, Okamura D, Li M, et al. "An alternative pluripotent state confers interspecies chimaeric competency." Nature. 2015;521(7552):316-21.
O'Brien EJ, Monk JM, Palsson BO. "Using Genome-scale Models to Predict Biological Capabilities." Cell. 2015;161(5):971-87.
Friedmann-Morvinski D, Bhargava V, Gupta S, Verma IM, Subramaniam S. "Identification of therapeutic targets for glioblastoma by network analysis." Oncogene. 2015.
Murrell B, Weaver S, Smith MD, et al. "Gene-wide identification of episodic selection." Mol. Biol. Evol.. 2015;32(5):1365-71.
DeBoever C, Ghia EM, Shepard PJ, et al. "Transcriptome sequencing reveals potential mechanism of cryptic 3' splice site selection in SF3B1-mutated cancers." PLoS Comput. Biol.. 2015;11(3):e1004105.
He Y, Ecker JR. "Non-CG Methylation in the Human Genome." Annu Rev Genomics Hum Genet. 2015.
Taheri-Araghi S, Brown SD, Sauls JT, McIntosh DB, Jun S. "Single-Cell Physiology." Annu Rev Biophys. 2015;44:123-42.
Schultz MD, He Y, Whitaker JW, et al. "Human body epigenome maps reveal noncanonical DNA methylation variation." Nature. 2015;523(7559):212-6.
Gross AM, Ideker T. "Molecular networks in context." Nat. Biotechnol.. 2015;33(7):720-1.
Lee SR, Pratt GA, Martinez FJ, Yeo GW, Lykke-Andersen J. "Target Discrimination in Nonsense-Mediated mRNA Decay Requires Upf1 ATPase Activity." Mol. Cell. 2015;59(3):413-25.
Choueiri MB, Shen JPaul, Gross AM, Huang JK, Ideker T, Fanta P. "ERCC1 and TS Expression as Prognostic and Predictive Biomarkers in Metastatic Colon Cancer." PLoS ONE. 2015;10(6):e0126898.
Gross AM, Cohen EEW. "Towards a personalized treatment of head and neck cancer." Am Soc Clin Oncol Educ Book. 2015;35:28-32.
Singh G, Pratt G, Yeo GW, Moore MJ. "The Clothes Make the mRNA: Past and Present Trends in mRNP Fashion." Annu. Rev. Biochem.. 2015;84:325-54.


Buganim Y, Markoulaki S, van Wietmarschen N, et al. "The developmental potential of iPSCs is greatly influenced by reprogramming factor selection." Cell Stem Cell. 2014;15(3):295-309.
Gross AM, Orosco RK, Shen JP, et al. "Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss." Nat. Genet.. 2014;46(9):939-43.
Hauff SJ, Raju SC, Orosco RK, et al. "Matrix-metalloproteinases in head and neck carcinoma-cancer genome atlas analysis and fluorescence imaging in mice." Otolaryngol Head Neck Surg. 2014;151(4):612-8.
McCorrison JM, Venepally P, Singh I, Fouts DE, Lasken RS, Methé BA. "NeatFreq: reference-free data reduction and coverage normalization for De Novo sequence assembly." BMC Bioinformatics. 2014;15(1):357. PMC 
Mukund K, Mathewson M, Minamoto V, Ward SR, Subramaniam S, Lieber RL. "Systems analysis of transcriptional data provides insights into muscle's biological response to botulinum toxin." Muscle Nerve. 2014;50(5):744-58.
Mollah SA, Dobrin JS, Feder RE, et al. "Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells." J. Invest. Dermatol.. 2014;134(5):1265-75.
Appleton E, Tao J, Haddock T, Densmore D. "Interactive assembly algorithms for molecular cloning." Nat. Methods. 2014;11(6):657-62.
Ma H, Morey R, O'Neil RC, et al. "Abnormalities in human pluripotent cells due to reprogramming mechanisms." Nature. 2014;511(7508):177-83.
Taheri-Araghi S, Bradde S, Sauls JT, et al. "Cell-Size Control and Homeostasis in Bacteria." Curr. Biol.. 2014.
Anandasabapathy N, Feder R, Mollah S, et al. "Classical Flt3L-dependent dendritic cells control immunity to protein vaccine." J. Exp. Med.. 2014;211(9):1875-91.
Lin MS, Cherny JJ, Fournier CT, Roth SJ, Krizanc D, Weir MP. "Assessment of MS/MS search algorithms with parent-protein profiling." J. Proteome Res.. 2014;13(4):1823-32.
Bhargava V, Head SR, Ordoukhanian P, Mercola M, Subramaniam S. "Technical Variations in Low-Input RNA-seq Methodologies." Sci Rep. 2014;4:3678. PMC 
Bean GJ, Jaeger PA, Bahr S, Ideker T. "Development of ultra-high-density screening tools for microbial "omics"." PLoS ONE. 2014;9(1):e85177. PMC 


Zhou D, Udpa N, Ronen R, et al. "Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders." Am. J. Hum. Genet.. 2013;93(3):452-62. PMC 
Ronen R, Udpa N, Halperin E, Bafna V. "Learning natural selection from the site frequency spectrum." Genetics. 2013;195(1):181-93. PMC 
Jung H, Bleazard T, Lee J, Hong D. "Systematic investigation of cancer-associated somatic point mutations in SNP databases." Nat. Biotechnol.. 2013;31(9):787-9.
Hua Z, Pool JE, Schmitz RJ, et al. "Epigenomic programming contributes to the genomic drift evolution of the F-Box protein superfamily in Arabidopsis." Proc. Natl. Acad. Sci. U.S.A.. 2013;110(42):16927-32. PMC 
Heinz S, Romanoski CE, Benner C, et al. "Effect of natural genetic variation on enhancer selection and function." Nature. 2013. PMC 
Behar M, Barken D, Werner SL, Hoffmann A. "The dynamics of signaling as a pharmacological target." Cell. 2013;155(2):448-61. PMC 
Schmitz RJ, He Y, Valdés-López O, et al. "Epigenome-wide inheritance of cytosine methylation variants in a recombinant inbred population." Genome Res.. 2013;23(10):1663-74. PMC 
Selvaraj S, Dixon JR, Bansal V, Ren B. "Whole-genome haplotype reconstruction using proximity-ligation and shotgun sequencing." Nat. Biotechnol.. 2013.
Wagner GA, Pacold ME, Kosakovsky Pond SL, et al. "Incidence and Prevalence of Intrasubtype HIV-1 Dual Infection in At-Risk Men in the United States." J. Infect. Dis.. 2013. PMC 
Jin F, Li Y, Dixon JR, et al. "A high-resolution map of the three-dimensional chromatin interactome in human cells." Nature. 2013;503(7475):290-4. PMC 
Hofree M, Shen JP, Carter H, Gross A, Ideker T. "Network-based stratification of tumor mutations." Nat. Methods. 2013;10(11):1108-15.
Xie W, Schultz MD, Lister R, et al. "Epigenomic analysis of multilineage differentiation of human embryonic stem cells." Cell. 2013;153(5):1134-48. PMC 
Schmitz RJ, Schultz MD, Urich MA, et al. "Patterns of population epigenomic diversity." Nature. 2013;495(7440):193-8. PMC 
Chang RL, Andrews K, Kim D, Li Z, Godzik A, Palsson BO. "Structural systems biology evaluation of metabolic thermotolerance in Escherichia coli." Science. 2013;340(6137):1220-3. PMC 
Nguyen D D, Wu C-H, Moree WJ, et al. "MS/MS networking guided analysis of molecule and gene cluster families." Proc. Natl. Acad. Sci. U.S.A.. 2013;110(28):E2611-20. PMC 
Woo S, Cha S W, Merrihew G, et al. "Proteogenomic Database Construction Driven from Large Scale RNA-seq Data." J. Proteome Res.. 2013. PMC 
Wagner GA, Pacold ME, Vigil E, et al. "Using ultradeep pyrosequencing to study HIV-1 coreceptor usage in primary and dual infection." J. Infect. Dis.. 2013;208(2):271-4. PMC 
Margeridon-Thermet S, Svarovskaia ES, Babrzadeh F, et al. "Low-level persistence of drug resistance mutations in hepatitis B virus-infected subjects with a past history of Lamivudine treatment." Antimicrob. Agents Chemother.. 2013;57(1):343-9. PMC 
Babrzadeh F, Varghese V, Pacold M, et al. "Collinearity of protease mutations in HIV-1 samples with high-level protease inhibitor class resistance." J. Antimicrob. Chemother.. 2013;68(2):414-8. PMC 
Allison KA, Kaikkonen MU, Gaasterland T, Glass CK. "Vespucci: a system for building annotated databases of nascent transcripts." Nucleic Acids Res.. 2013. PMC 
Chaillon A, Wagner GA, Hepler LN, et al. "Dynamics of Viral Evolution and Neutralizing Antibody Response after HIV-1 Superinfection." J. Virol.. 2013;87(23):12737-44. PMC 
Lovci MT, Ghanem D, Marr H, et al. "Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges." Nat. Struct. Mol. Biol.. 2013;20(12):1434-42.
Lister R, Mukamel EA, Nery JR, et al. "Global epigenomic reconfiguration during mammalian brain development." Science. 2013;341(6146):1237905. PMC 
Latif H, Lerman JA, Portnoy VA, et al. "The genome organization of Thermotoga maritima reflects its lifestyle." PLoS Genet.. 2013;9(4):e1003485. PMC 
Feldman KE, Loriaux PM, Saito M, et al. "Ex vivo innate immune cytokine signature of enhanced risk of relapsing brucellosis." PLoS Negl Trop Dis. 2013;7(9):e2424. PMC 
Hu M, Deng K, Qin Z, et al. "Bayesian inference of spatial organizations of chromosomes." PLoS Comput. Biol.. 2013;9(1):e1002893. PMC 
Bhargava V, Ko P, Willems E, Mercola M, Subramaniam S. "Quantitative transcriptomics using designed primer-based amplification." Sci Rep. 2013;3:1740. PMC 
Ebrahim A, Lerman JA, Palsson BO, Hyduke DR. "COBRApy: COnstraints-Based Reconstruction and Analysis for Python." BMC Syst Biol. 2013;7:74. PMC 
O'Brien EJ, Lerman JA, Chang RL, Hyduke DR, Palsson BØ. "Genome-scale models of metabolism and gene expression extend and refine growth phenotype prediction." Mol. Syst. Biol.. 2013;9:693. PMC 
Chang RL, Xie L, Bourne PE, Palsson BO. "Antibacterial mechanisms identified through structural systems pharmacology." BMC Syst Biol. 2013;7:102. PMC 
Hightower GK, May SJ, Pérez-Santiago J, et al. "HIV-1 clade B pol evolution following primary infection." PLoS ONE. 2013;8(6):e68188. PMC 
Nakatsuji T, Chiang H-I, Jiang SB, Nagarajan H, Zengler K, Gallo RL. "The microbiome extends to subepidermal compartments of normal skin." Nat Commun. 2013;4:1431. PMC 


Ho Sui SJ, Lo R, Fernandes AR, et al. "Raloxifene attenuates Pseudomonas aeruginosa pyocyanin production and virulence." Int. J. Antimicrob. Agents. 2012;40(3):246-51.
Wilbert ML, Huelga SC, Kapeli K, et al. "LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance." Mol. Cell. 2012;48(2):195-206. PMC 
Ruiz S, Diep D, Gore A, et al. "Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells." Proc. Natl. Acad. Sci. U.S.A.. 2012;109(40):16196-201. PMC 
Prlić A, Yates A, Bliven SE, et al. "BioJava: an open-source framework for bioinformatics in 2012." Bioinformatics. 2012;28(20):2693-5. PMC 
Baycin-Hizal D, Tabb DL, Chaerkady R, et al. "Proteomic analysis of Chinese hamster ovary cells." J. Proteome Res.. 2012;11(11):5265-76. PMC 
Lagier-Tourenne C, Polymenidou M, Hutt KR, et al. "Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs." Nat. Neurosci.. 2012;15(11):1488-97. PMC 
Dixon JR, Selvaraj S, Yue F, et al. "Topological domains in mammalian genomes identified by analysis of chromatin interactions." Nature. 2012;485(7398):376-80. PMC 
Bernard A, Lubbers LS, Tanis KQ, et al. "Transcriptional architecture of the primate neocortex." Neuron. 2012;73(6):1083-99. PMC 
Diep D, Plongthongkum N, Gore A, Fung H-L, Shoemaker R, Zhang K. "Library-free methylation sequencing with bisulfite padlock probes." Nat. Methods. 2012;9(3):270-2. PMC 
Ronen R, Boucher C, Chitsaz H, Pevzner P. "SEQuel: improving the accuracy of genome assemblies." Bioinformatics. 2012;28(12):i188-96. PMC 
Dixon-Salazar TJ, Silhavy JL, Udpa N, et al. "Exome sequencing can improve diagnosis and alter patient management." Sci Transl Med. 2012;4(138):138ra78.
Prindle A, Samayoa P, Razinkov I, Danino T, Tsimring LS, Hasty J. "A sensing array of radically coupled genetic 'biopixels'." Nature. 2012;481(7379):39-44. PMC 
Cho B-K, Federowicz S, Park Y-S, Zengler K, Palsson BØ. "Deciphering the transcriptional regulatory logic of amino acid metabolism." Nat. Chem. Biol.. 2012;8(1):65-71. PMC 
Gendron JM, Pruneda-Paz JL, Doherty CJ, Gross AM, S Kang E, Kay SA. "Arabidopsis circadian clock protein, TOC1, is a DNA-binding transcription factor." Proc. Natl. Acad. Sci. U.S.A.. 2012;109(8):3167-72.
Yamaguchi S, Hong K, Liu R, et al. "Tet1 controls meiosis by regulating meiotic gene expression." Nature. 2012;492(7429):443-7. PMC 
Hu M, Deng K, Selvaraj S, Qin Z, Ren B, Liu JS. "HiCNorm: removing biases in Hi-C data via Poisson regression." Bioinformatics. 2012;28(23):3131-3. PMC 
Shih VF-S, Davis-Turak J, Macal M, et al. "Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways." Nat. Immunol.. 2012;13(12):1162-70. PMC 
Schultz MD, Schmitz RJ, Ecker JR. "'Leveling' the playing field for analyses of single-base resolution DNA methylomes." Trends Genet.. 2012;28(12):583-5. PMC 
Nam H, Lewis NE, Lerman JA, et al. "Network context and selection in the evolution to enzyme specificity." Science. 2012;337(6098):1101-4. PMC 
Konopka G, Friedrich T, Davis-Turak J, et al. "Human-specific transcriptional networks in the brain." Neuron. 2012;75(4):601-17. PMC 
Johnson DBF, Wang C, Xu J, et al. "Release factor one is nonessential in Escherichia coli." ACS Chem. Biol.. 2012;7(8):1337-44. PMC 
Lewis NE, Nagarajan H, Palsson BO. "Constraining the metabolic genotype-phenotype relationship using a phylogeny of in silico methods." Nat. Rev. Microbiol.. 2012;10(4):291-305. PMC 
Kurihara Y, Schmitz RJ, Nery JR, et al. "Surveillance of 3' Noncoding Transcripts Requires FIERY1 and XRN3 in Arabidopsis." G3 (Bethesda). 2012;2(4):487-98. PMC 
Bliven S, Prlić A. "Circular permutation in proteins." PLoS Comput. Biol.. 2012;8(3):e1002445. PMC 
Lerman JA, Hyduke DR, Latif H, et al. "In silico method for modelling metabolism and gene product expression at genome scale." Nat Commun. 2012;3:929. PMC 
Thiele I, Fleming RMT, Que R, Bordbar A, Diep D, Palsson BO. "Multiscale modeling of metabolism and macromolecular synthesis in E. coli and its application to the evolution of codon usage." PLoS ONE. 2012;7(9):e45635. PMC 
He Y, Zhang Y, Zheng G, Wei C. "CTF: a CRF-based transcription factor binding sites finding system." BMC Genomics. 2012;13 Suppl 8:S18. PMC 
Huelga SC, Yeo GW. "Genomics of Alternative Splicing in Stem Cells.". In: Computational Biology of Embryonic Stem Cells (Ming Zhan, Ed.), pp. 147-160. Oak Park, IL: Bentham Science Publishers; 2012.


Schmitz RJ, Schultz MD, Lewsey MG, et al. "Transgenerational epigenetic instability is a source of novel methylation variants." Science. 2011;334(6054):369-73. PMC 
Johnson DBF, Xu J, Shen Z, et al. "RF1 knockout allows ribosomal incorporation of unnatural amino acids at multiple sites." Nat. Chem. Biol.. 2011;7(11):779-86. PMC 
Diep D, Zhang K. "Genome-wide mapping of the sixth base." Genome Biol.. 2011;12(6):116. PMC 
Zhou D, Udpa N, Gersten M, et al. "Experimental selection of hypoxia-tolerant Drosophila melanogaster." Proc. Natl. Acad. Sci. U.S.A.. 2011;108(6):2349-54. PMC 
Cho B-K, Federowicz SA, Embree M, Park Y-S, Kim D, Palsson BØ. "The PurR regulon in Escherichia coli K-12 MG1655." Nucleic Acids Res.. 2011;39(15):6456-64. PMC 
Hansen K D, Timp W, Bravo H C, et al. "Increased methylation variation in epigenetic domains across cancer types." Nat. Genet.. 2011;43(8):768-75. PMC 
Xu X, Nagarajan H, Lewis NE, et al. "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line." Nat. Biotechnol.. 2011;29(8):735-41. PMC 
Liu G-H, Barkho BZ, Ruiz S, et al. "Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome." Nature. 2011;472(7342):221-5. PMC 
Polymenidou M, Lagier-Tourenne C, Hutt KR, et al. "Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43." Nat. Neurosci.. 2011;14(4):459-68. PMC 
Chang RL, Ghamsari L, Manichaikul A, et al. "Metabolic network reconstruction of Chlamydomonas offers insight into light-driven algal metabolism." Mol. Syst. Biol.. 2011;7:518. PMC 
Orth JD, Conrad TM, Na J, et al. "A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011." Mol. Syst. Biol.. 2011;7:535. PMC 
Charusanti P, Chauhan S, McAteer K, et al. "An experimentally-supported genome-scale metabolic network reconstruction for Yersinia pestis CO92." BMC Syst Biol. 2011;5:163. PMC 
Udpa N, Zhou D, Haddad GG, Bafna V. "Tests of selection in pooled case-control data: an empirical study." Front Genet. 2011;2:83. PMC 


Lerman J, Palsson BO. "Microbiology. Topping off a multiscale balancing act." Science. 2010;330(6007):1058-9.
Brinza D, Schultz M, Tesler G, Bafna V. "RAPID detection of gene-gene interactions in genome-wide association studies." Bioinformatics. 2010;26(22):2856-62. PMC 
Hawkins DR, Hon GC, Lee LK, et al. "Distinct epigenomic landscapes of pluripotent and lineage-committed human cells." Cell Stem Cell. 2010;6(5):479-91. PMC 
Feist AM, Zielinski DC, Orth JD, Schellenberger J, Herrgard MJ, Palsson BØ. "Model-driven evaluation of the production potential for growth-coupled products of Escherichia coli." Metab. Eng.. 2010;12(3):173-86. PMC 
Hughey JJ, Lee TK, Covert MW. "Computational modeling of mammalian signaling networks." Wiley Interdiscip Rev Syst Biol Med. 2010;2(2):194-209. PMC 
Grubisic I, Shokhirev MN, Orzechowski M, Miyashita O, Tama F. "Biased coarse-grained molecular dynamics simulation approach for flexible fitting of X-ray structure into cryo electron microscopy maps." J. Struct. Biol.. 2010;169(1):95-105.
König R, Stertz S, Zhou Y, et al. "Human host factors required for influenza virus replication." Nature. 2010;463(7282):813-7. PMC 
Prlic A, Bliven S, Rose PW, et al. "Pre-calculated protein structure alignments at the RCSB PDB website." Bioinformatics. 2010;26(23):2983-5. PMC 
Pacold M, Smith D, Little S, et al. "Comparison of methods to detect HIV dual infection." AIDS Res. Hum. Retroviruses. 2010;26(12):1291-8. PMC 
Chang RL, Luo F, Johnson S, Scheuermann RH. "Deterministic graph-theoretic algorithm for detecting modules in biological interaction networks." Int J Bioinform Res Appl. 2010;6(2):101-19.
Chang RL, Xie L, Xie L, Bourne PE, Palsson BØ. "Drug off-target effects predicted using structural analysis in the context of a metabolic network model." PLoS Comput. Biol.. 2010;6(9):e1000938. PMC 
Cohen T, G Whitfield K, Schvaneveldt RW, Mukund K, Rindflesch T. "EpiphaNet: An Interactive Tool to Support Biomedical Discoveries." J Biomed Discov Collab. 2010;5:21-49.


Fossum E, Friedel CC, Rajagopala SV, et al. "Evolutionarily conserved herpesviral protein interaction networks." PLoS Pathog.. 2009;5(9):e1000570. PMC 
Smith DM, May SJ, Pérez-Santiago J, et al. "The use of pooled viral load testing to identify antiretroviral treatment failure." AIDS. 2009;23(16):2151-8. PMC 
Hon GC, Hawkins DR, Ren B. "Predictive chromatin signatures in the mammalian genome." Hum. Mol. Genet.. 2009;18(R2):R195-201. PMC 
Tsai K-C, Teng L-W, Shao Y-M, et al. "The first pharmacophore model for potent NF-kappaB inhibitors." Bioorg. Med. Chem. Lett.. 2009;19(19):5665-9.
Terzer M, Maynard ND, Covert MW, Stelling J. "Genome-scale metabolic networks." Wiley Interdiscip Rev Syst Biol Med. 2009;1(3):285-97.
Sears DD, Hsiao G, Hsiao A, et al. "Mechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization." Proc. Natl. Acad. Sci. U.S.A.. 2009;106(44):18745-50. PMC 
Lister R, Pelizzola M, Dowen RH, et al. "Human DNA methylomes at base resolution show widespread epigenomic differences." Nature. 2009;462(7271):315-22. PMC 
Hon G, Wang W, Ren B. "Discovery and annotation of functional chromatin signatures in the human genome." PLoS Comput. Biol.. 2009;5(11):e1000566. PMC 
Heintzman ND, Hon GC, Hawkins DR, et al. "Histone modifications at human enhancers reflect global cell-type-specific gene expression." Nature. 2009;459(7243):108-12. PMC 
Loriaux P, Hoffmann A. "Of elections and cell-death decisions." Mol. Cell. 2009;34(3):257-8. PMC 
Bushman FD, Malani N, Fernandes J, et al. "Host cell factors in HIV replication: meta-analysis of genome-wide studies." PLoS Pathog.. 2009;5(5):e1000437. PMC 
Veretnik S, Wills C, Youkharibache P, Valas RE, Bourne PE. "Sm/Lsm genes provide a glimpse into the early evolution of the spliceosome." PLoS Comput. Biol.. 2009;5(3):e1000315. PMC 
Liu W-T, Ng J, Meluzzi D, et al. "Interpretation of tandem mass spectra obtained from cyclic nonribosomal peptides." Anal. Chem.. 2009;81(11):4200-9. PMC 
Wang H, Kakaradov B, Collins SR, et al. "A complex-based reconstruction of the Saccharomyces cerevisiae interactome." Mol. Cell Proteomics. 2009;8(6):1361-81. PMC 
Valas RE, Yang S, Bourne PE. "Nothing about protein structure classification makes sense except in the light of evolution." Curr. Opin. Struct. Biol.. 2009;19(3):329-34. PMC 
Hsiao A, Kuo MD. "High-throughput biology in the postgenomic era." J Vasc Interv Radiol. 2009;20(7 Suppl):S488-96.
Kim S, Gupta N, Bandeira N, Pevzner PA. "Spectral dictionaries: Integrating de novo peptide sequencing with database search of tandem mass spectra." Mol. Cell Proteomics. 2009;8(1):53-69. PMC 
Chaisson MJ, Brinza D, Pevzner PA. "De novo fragment assembly with short mate-paired reads: Does the read length matter?" Genome Res.. 2009;19(2):336-46. PMC 
Feist AM, Herrgård MJ, Thiele I, Reed JL, Palsson BØ. "Reconstruction of biochemical networks in microorganisms." Nat. Rev. Microbiol.. 2009;7(2):129-43. PMC 
Li F, Thiele I, Jamshidi N, Palsson BØ. "Identification of potential pathway mediation targets in Toll-like receptor signaling." PLoS Comput. Biol.. 2009;5(2):e1000292. PMC 
Butler DM, Pacold ME, Jordan PS, Richman DD, Smith DM. "The efficiency of single genome amplification and sequencing is improved by quantitation and use of a bioinformatics tool." J. Virol. Methods. 2009;162(1-2):280-3. PMC 
Ng J, Bandeira N, Liu W-T, et al. "Dereplication and de novo sequencing of nonribosomal peptides." Nat. Methods. 2009;6(8):596-9. PMC 
Manichaikul A, Ghamsari L, Hom EFY, et al. "Metabolic network analysis integrated with transcript verification for sequenced genomes." Nat. Methods. 2009;6(8):589-92. PMC 
Seok J, Xiao W, Moldawer LL, Davis RW, Covert MW. "A dynamic network of transcription in LPS-treated human subjects." BMC Syst Biol. 2009;3:78. PMC 
Lee TK, Denny EM, Sanghvi JC, et al. "A noisy paracrine signal determines the cellular NF-kappaB response to lipopolysaccharide." Sci Signal. 2009;2(93):ra65. PMC 
DeBlasio D, Bruand J, Zhang S. "PMFastR: A New Approach to Multiple RNA Structure Alignment." In: Salzberg S, Warnow T, eds. Algorithms in Bioinformatics, 9th International Workshop, WABI 2009, Philadelphia, PA, USA, September 12-13, 2009. Proceedings. Springer; 2009.
Yang S, Valas R, Bourne PE. "Evolution Studied Using Protein Structure." In: Gu J, Bourne P, eds. Structural Bioinformatics (Methods of Biochemical Analysis), pp. 559-571. 2nd ed. Hoboken, N.J.: Wiley & Sons, Inc.; 2009. Publisher  Amazon 


Chen WY-C, Chen P-Y, Chen CY-C, Chung J-G. "Exploring 3D-QSAR pharmacophore mapping of azaphenanthrenone derivatives for mPGES-1 inhibition Using HypoGen technique.". In: Computational Intelligence in Bioinformatics and Computational Biology, 2008. CIBCB '08. IEEE Symposium on.; 2008.
Chen OY-C, Chen G-W, Chen WY-C. "A novel strategy for the structure-based drug design of heat shock protein 90 inhibitors.". In: Neural Networks, 2008. IJCNN 2008. (IEEE World Congress on Computational Intelligence). IEEE International Joint Conference on.; 2008.
Covert MW, Xiao N, Chen TJ, Karr JR. "Integrating metabolic, transcriptional regulatory and signal transduction models in Escherichia coli." Bioinformatics. 2008;24(18):2044-50.
Dost B, Shlomi T, Gupta N, Ruppin E, Bafna V, Sharan R. "QNet: a tool for querying protein interaction networks." J. Comput. Biol.. 2008;15(7):913-25.
Shlomi T, Cabili MN, Herrgård MJ, Palsson BØ, Ruppin E. "Network-based prediction of human tissue-specific metabolism." Nat. Biotechnol.. 2008;26(9):1003-10.
Roguev A, Bandyopadhyay S, Zofall M, et al. "Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast." Science. 2008;322(5900):405-10. PMC 
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